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The collaboration between SciSparc Ltd. and Clearmind Medicine Inc. has led to the publication of a patent application for a combination treatment using MEAI and PEA for treating cocaine addiction, based on preclinical trial results demonstrating significant reduction in cocaine-induced craving without impairing natural rewards. The study suggests that MEAI's effect on drug craving is specifically targeted at drug-related compulsions rather than the general reward system. This latest publication adds to multiple patent applications filed as part of their ongoing collaboration.

The US and Ukrainian officials will meet in Saudi Arabia this week to discuss the timing and scope of an initial ceasefire with Russia, with multiple points of tension still to be ironed out. The planned talks follow intense pressure by President Trump's administration on Ukrainian leader Volodymyr Zelenskiy, including the suspension of military aid and intelligence assistance. An economic agreement between Washington and Kyiv on Ukraine's natural resources has been tied to securing a truce commitment.

Cryptocurrency prices have continued their downward trend due to escalating tariff war tensions and diminishing prospects of further Federal Reserve rate cuts, outweighing the pro-crypto announcements from President Donald Trump last week. The uncertainty surrounding these economic factors has led to a decrease in investor confidence, with Bitcoin falling as much as 3.7% early on Monday. Despite recent developments that have given investors a more bullish outlook, macroeconomic headwinds are still dominating the crypto market.

The Trump administration's freeze on USDA grants and loans is creating financial turmoil for farmers, with many halting investments and facing potential bankruptcy due to uncertainty in agricultural funding. This decision has disrupted agricultural markets, leading to confusion and stress in farming communities that have historically supported Trump. As farmers await the release of frozen funds, the long-term implications for the agricultural sector and its economic stability remain unclear.

HSBC has downgraded its outlook on U.S. equities to "neutral" amid uncertainty surrounding the Trump administration's trade policies, while upgrading its rating on European stocks to "overweight". The brokerage believes a proposed $1.2 trillion European fiscal package and China's emergence as a tech leader are shifting investor capital away from the United States. The S&P 500 has pulled back 6.1% since its record high in February, with worries about trade war impacts on corporate profits and growth.

The Antec Core HS A7840U offers a unique combination of features that set it apart from other handheld gaming consoles, making it an attractive option for those seeking a portable workstation. Powered by the AMD Ryzen 7 7840U processor and Radeon 780M mobile graphics, this device provides a balance between gaming performance and productivity capabilities. Its compact design and docking station feature make it an excellent choice for anyone looking to stay productive on-the-go.

Rocket Cos.'s acquisition of Redfin Corp., valued at $1.75 billion, signals a significant shift in the property market as the financial technology group delves deeper into the industry with a new listing site. The deal represents a premium of 63% over Redfin's common stock price, indicating investor confidence in Rocket's ability to integrate home search with its existing platform. By acquiring Redfin, Rocket aims to accelerate its purchase and AI strategy, aiming for $200 million in run-rate synergies by 2027.

Cocoro (COCORO), the new meme coin launched by Own the DOGE, the group behind the original Doge meme's intellectual property, has made its debut on Base, the Ethereum layer-2 network developed by Coinbase. The coin's market cap surged past $80 million after its launch, but dropped to around $46 million with a token price near $0.046. COCORO's tokenomics feature 75% of the supply locked into liquidity pools, 20% distributed via airdrops to DOG and NEIRO holders.

When selecting a game controller for PC gaming, consumers face a multitude of choices that can be overwhelming, but understanding the options is key to making an informed decision. Xbox controllers offer the best out-of-the-box compatibility for Windows PCs, while PlayStation controllers come with caveats that may complicate their use on various platforms. Additionally, third-party controllers provide unique features and customization options, catering to diverse gaming preferences and needs.

Applied Materials, Inc. has increased its quarterly cash dividend by 15 percent, marking eight consecutive years of higher dividends, with a new share repurchase authorization enabling the company to buy back an additional $10 billion of its shares over time. The increase in dividend payout reflects the company's confidence in its business prospects and its ability to distribute excess cash to shareholders. This move also underscores Applied Materials' commitment to returning value to its investors.

Microsoft's next major home console might be more like a PC, with a TV-friendly shell, according to a recent rumor. This would make it similar to a Steam Machine, allowing players greater freedom over their gaming experience. The concept challenges the traditional console market and raises questions about the future of gaming.

Modi will reiterate Mauritius sovereign rights over Chagos, Trump has indicated support to UK-Mauritius deal over islands. India, Mauritius to sign agreement to enhance maritime security. The move reflects a shift in regional dynamics, as India seeks to bolster its strategic partnerships with island nations against the growing influence of China.

The Kremlin has dismissed Western accusations of Russian sabotage in the U.S. and Europe as "empty and ephemeral" and without evidence. These claims have been repeatedly made by NATO allies, including Britain's foreign spy chief, but the Kremlin insists that Russia has not engaged in any such activities. The accusations have also led to suspensions of certain measures to counter alleged Russian sabotage campaigns.

Britain is concerned by China's "dangerous and destabilising" activity in the South China Sea, with British Foreign Minister David Lammy stating that the UK and world economy depend on these trade routes being safe and secure. The Philippines is particularly at risk, facing frequent challenges to freedom of navigation and international law. The situation has raised tensions in the region, with the US previously condemning a Chinese navy helicopter's manoeuvres that endangered a Philippine government aircraft.

The Singapore Exchange plans to list bitcoin perpetual futures in the second half of 2025, targeting institutional clients and professional investors, in a move that could significantly expand market access for this asset class. The firm's offering is expected to bring retail customers into the picture, potentially creating a new level of volatility in the markets. However, no specific details have been provided on how the exchange intends to ensure regulatory compliance with existing laws and regulations.

German industrial output experienced a 2.0% increase in January, yet exports declined by 2.5%, highlighting the significant challenges the new government faces in revitalizing the economy amidst geopolitical uncertainty. Despite the rise in production, which surpasses prior quarter averages, concerns persist over the overall stagnation in the industrial sector, as production remains approximately 10% below pre-pandemic levels. Analysts remain cautious, emphasizing that while the rise in production may indicate a potential bottoming out of the industrial slump, a substantial recovery is not yet assured.

Energy executives gathering for CERAWeek in Houston are grappling with the complexities of President Donald Trump's policies, which have sparked both hope and uncertainty within the fossil fuel sector. While Trump's administration has lifted certain restrictions and promised increased production, the economic instability caused by his tariffs and sanctions has led to declining oil prices and potential disruptions in investment strategies. As the industry faces a challenging landscape, the conference is expected to reflect a mix of enthusiasm for regulatory support and anxiety over the unpredictable economic climate.

KalVista Pharmaceuticals will host a virtual event on March 25, 2025, to provide an overview of its commercialization strategy for sebetralstat, an investigational treatment for hereditary angioedema (HAE). The company has completed Marketing Authorization Applications for sebetralstat to global regulatory authorities and is under regulatory review by the U.S. FDA. Sebetralstat is under investigation for its safety and efficacy in treating HAE.

The shifting dynamics of global manufacturing and supply chain strategies have created an unprecedented moment of change for logistics professionals, businesses, and policymakers alike. As companies respond to rising labor costs, trade policy uncertainties, and geopolitical tensions, the execution of diversification strategies is far from simple. From infrastructure limitations and workforce shortages to regulatory hurdles and freight market volatility, manufacturers face a multitude of challenges in repositioning their global manufacturing footprint.

UNA Watch introduces a modular and sustainable alternative in the wearable technology space, allowing users to replace individual components like batteries and screens, akin to building with Lego. Backed by a £300,000 investment, the Edinburgh-based company aims to challenge the disposability of current wearables, exemplified by the Apple Watch's design limitations. With features such as GPS, health monitoring, and a 10-day battery life, the UNA Watch is set to launch on Kickstarter, attracting significant early interest.

Microsoft is testing new features for Windows 11 that include app recommendations in the Start menu and suggested files in File Explorer, aimed at enhancing user experience. The Start menu will now suggest apps typically used together, while File Explorer will display relevant files based on user activity, although these changes will not be available in the European Economic Area for now. While some users may find these recommendations helpful, others may view them as unnecessary clutter in the interface.

Hungary is seeking to expand its energy cooperation with Romania, driven in part by its desire to reduce dependence on Russian gas and explore new supply sources. The two countries are negotiating an agreement that could pave the way for increased trade and collaboration in the energy sector. This development reflects Hungary's efforts to diversify its energy mix and enhance its energy security.

Protalix BioTherapeutics, Inc. will release its financial results for the fiscal year ended December 31, 2024, and provide a business and clinical update on March 17, 2025, marking a significant milestone in the company's journey as it continues to push the boundaries of recombinant therapeutic protein development. The announcement comes after Protalix has already gained FDA approval for its innovative ProCellEx plant cell-based expression system, paving the way for future product launches. As the company looks to the future, investors and stakeholders will be eagerly awaiting insights into its progress.

European lawmakers are voicing fresh doubt about the European Central Bank’s ability to deliver its digital euro project following an outage in the ECB’s existing payment system. The breakdown in Target 2 (T2) caused delays for thousands of households and traders, raising concerns about the ECB's credibility. A successful digital euro would require restoring citizens' trust, with lawmakers emphasizing the need for improved systems and secure financial infrastructure.

Meredith Whittaker, President of Signal, has raised alarms about the security and privacy risks associated with agentic AI, describing its implications as "haunting." She argues that while these AI agents promise convenience, they require extensive access to user data, which poses significant risks if such information is compromised. The integration of AI agents with messaging platforms like Signal could undermine the end-to-end encryption that protects user privacy.

Justine Musk, the first wife of billionaire Elon Musk, once shared her unique insights on the journey to becoming a billionaire. In 2015, Justine Musk responded to a Quora thread questioning whether determination and hard work alone lead to a billion-dollar fortune. She firmly answered, "No," emphasizing that determination falls short of the mark; instead, one must be ready to tackle extreme challenges head-on.

US stock index futures fell on Monday as worries persisted that tit-for-tat tariffs could affect the world's largest economy, while electric-vehicle maker Tesla declined following a bearish brokerage forecast. The decline in US-listed shares of Chinese companies also fell due to weak economic data, leading to a drop in crypto stocks. Companies such as Airbnb climbed on bullish brokerage ratings, providing some relief. Futures were down for the Dow, S&P 500, and Nasdaq.

U.S. stock index futures fell on Monday as worries persisted that the Trump administration's tariff policies could affect the world's largest economy, while EV maker Tesla declined following a bearish brokerage forecast. The benchmark S&P 500 logged its biggest weekly drop since September on Friday and the tech-heavy Nasdaq fell more than 10% from its December record high on Thursday. Investors will be watching closely for data on inflation, job openings and consumer confidence later in the week.

U.S. stock index futures have dropped amid ongoing fears that escalating tariffs may negatively impact the economy, with Tesla's stock declining following a bearish forecast from UBS. Major tech companies, including Nvidia, Meta, and Amazon, also experienced declines as investors shifted towards safer assets like Treasury bonds. The volatility in the market is exacerbated by uncertainty surrounding President Trump's trade policies, which have raised recession fears among economists.

Aspen Pharmacare Holdings Limited's ( JSE:APN ) stock was strong despite it releasing a soft earnings report last week. Our analysis suggests that investors may have noticed some promising signs beyond the statutory profit figures. The company's unusual items, which reduced its statutory profit by R1.9b, may not be repeated in the future, potentially leading to an improvement in its profit.

Iran has rejected U.S. President Donald Trump's letter urging the country to negotiate a nuclear deal, citing its own policy positions and sovereignty in foreign affairs. The Kremlin has confirmed no consultations were held with Iran before or after the letter was sent. Kremlin spokesman Dmitry Peskov emphasized that Iran seeks negotiations based on mutual respect and constructive dialogue.

A sea change in German fiscal policy is rapidly transforming global bond markets as it is expected to increase the pool of top-rated, safe-haven debt and propel Germany into a new era of structurally higher government bond yields. Companies and investors are excited by this shift, anticipating a surge in bond sales to fund increased spending. The increase in 10-year Bund yield has already had knock-on effects on global yields.

North Korea has fired multiple ballistic missiles off its west coast, marking the first such launch since Donald Trump's return to power, as Pyongyang shows no signs of holding back from its missile testing amid heightened tensions with Washington and Seoul. The launch comes amid ongoing diplomatic uncertainty in South Korea, following President Yoon Suk Yeol's brief imposition of martial law in December and his subsequent impeachment. The projectiles were likely close-range ballistic missiles, launched from the Hwanghae Province in North Korea's west.

The Spark 2 from Positive Grid embodies the "software-ization" of music, marrying digital modeling with portable hardware to create an affordable and versatile solution for musicians. This miniature old-school amp is, in essence, a computer with knobs and a speaker, leveraging firmware updates, DSP chips, and smartphone apps to deliver a vast array of guitar tones. Digital amp modeling has revolutionized the music industry, offering home musicians unparalleled access to high-quality gear at a fraction of the cost.

The odds of a wider market meltdown are decreasing as the S&P 500 Index's controlled decline reduces investor exposure, according to Nomura Securities cross-asset strategist Charlie McElligott. The latest choppiness in markets has been accompanied by "appropriate mechanical de-allocation, deleveraging and rebalancing trades that remove accelerant flows which then contribute to crash conditions," McElligott wrote in a note. With most assets under management remaining focused on tech leadership, the strategist expects volatility to decline in the coming weeks if an idiosyncratic shock is absent.

HUTCHMED (China) Limited, a Chinese pharmaceutical company, has delivered strong revenue growth over the last three years, with annual increases of 34%. The company's share price has also risen steadily, up 4% per year during this period. This performance is impressive, especially considering HUTCHMED (China)'s lack of profitability.

Novo Nordisk has announced promising results from the REDEFINE 2 trial, which evaluated the efficacy and safety of CagriSema, a combination treatment for obesity and type 2 diabetes. The trial showed that 61.9% of participants on CagriSema experienced a weight loss of 15.7% after 68 weeks, significantly outperforming the placebo group's 3.1% weight loss. Novo Nordisk plans to seek regulatory approval for CagriSema in early 2026, aiming to provide an effective treatment option for millions affected by obesity.

Gold steadied on Monday as a stronger U.S. dollar countered safe-haven demand amid trade war concerns, while investors looked to inflation data this week for clues on the Federal Reserve's next interest rate decision. Spot gold was at $2,913.09 an ounce at 0946 GMT, while U.S. gold futures firmed 0.2% to $2,920.10. The dollar index held above last week's four-month low, making gold more expensive for holders of other currencies.

An outage on Elon Musk's social media platform X appeared to ease after thousands of users in the U.S. and the UK reported glitches on Monday, according to outage-tracking website Downdetector.com. The number of reports in the U.S. dropped to 403 as of 6:24 a.m. ET from more than 21,000 incidents earlier, user-submitted data on Downdetector showed. Reports in the UK also decreased significantly, with around 200 incidents reported compared to 10,800 earlier.

Democratic Republic of Congo's former President Joseph Kabila has faced increasing pressure over Rwanda-backed rebels' advances in the east, prompting officials from his party to be questioned by a military prosecutor. Kabila had reached out to opposition politicians and civil society members to discuss the country's political future, amid criticism of Tshisekedi's response to M23's military campaign. The exact reason for the invitations was not clear, but President Felix Tshisekedi has recently accused Kabila of sponsoring the M23 rebels.

Global hedge funds have reversed course, selling China equities for a fourth straight week as renewed enthusiasm for Chinese tech stocks ignited by low-cost artificial intelligence startup DeepSeek began to fade. The sell-off is attributed to decelerating trade growth and worsening deflationary pressures reflected in latest data. Hedge funds' net allocation to Chinese equities remains relatively light, ranking in the 37th percentile over the past five years.

Global hedge funds have continued to sell China equities for a fourth straight week as renewed enthusiasm for Chinese tech stocks ignited by low-cost artificial intelligence startup DeepSeek began to fade. Hedge funds have reversed course since mid-February, cutting long positions and adding short bets, according to Goldman Sachs prime brokerage. The investment bank estimates that hedge fund positions on China remain relatively light, with net allocation ranking in the 37th percentile over the past five years.

Ukraine is under US pressure to accept a quick truce to end the war with Russia, with senior US officials believing the country's leadership is "ready to move forward" with the US's demand for a ceasefire process. The Trump administration has stepped up pressure on Ukrainian President Volodymyr Zelensky to accept his demands for a rapid ceasefire with Moscow, despite doubts about Ukraine's willingness to negotiate. A meeting between US and Ukrainian officials is set to take place in Saudi Arabia, where the two sides are expected to discuss a framework for peace.

The Indian rupee weakened on Monday due to strong demand to buy dollars at the daily reference rate and a decline in the Chinese yuan amid worries about its economy and global trade war. The rupee declined 0.4% to 87.26 against the U.S. dollar as of 9:45 a.m. IST, with the reference rate quoting at a 1/1.20 paisa premium. The dollar index ticked up to 103.8, recovering from a four-month low hit last week.

AstraZeneca has announced promising results from the Phase III MATTERHORN trial of Imfinzi in combination with FLOT chemotherapy for patients with resectable gastric and gastroesophageal junction cancers. The trial demonstrated a statistically significant improvement in event-free survival, marking a notable achievement as the first Phase III study of an immunotherapy to reach this endpoint for these cancer types. With positive interim findings suggesting a trend towards overall survival, AstraZeneca emphasizes the potential of early-stage interventions to significantly impact patient outcomes.

The "Locksmiths in the United States and Canada" report provides an in-depth analysis of the locksmith industry, highlighting operational structures, financial insights, and emerging trends. It serves as a valuable resource for industry professionals, equipping them with actionable information to navigate risks and capitalize on future opportunities. With features such as financial benchmarks and quarterly insights, the report aims to establish trust and expertise among its users.

Greenland's Prime Minister Mute Egede has criticized U.S. President Donald Trump's renewed interest in acquiring the mineral-rich island, claiming it reflects a lack of respect for Greenlanders. In response to Trump's promises of prosperity and safety, Egede emphasized that Greenland deserves to be treated as an autonomous entity with the right to determine its own future. As the island approaches a general election, public sentiment shows a strong preference against U.S. annexation, with many viewing Trump's overtures as a potential threat.

Money market account interest rates have risen significantly, with some accounts offering returns as high as 4.51% APY, providing a compelling option for savers seeking liquidity and growth. Despite a recent downward trend following the Federal Reserve's rate cuts, many online banks and credit unions continue to offer competitive rates, making it essential for consumers to shop around for the best options. As interest rates have fluctuated in response to economic conditions, understanding the nuances of money market accounts, including fees and minimum balance requirements, remains crucial for maximizing savings.

If you were lucky enough to receive a DOGE dividend payout of $5,000 from President Trump's Department of Government Efficiency (DOGE), consider prioritizing building an emergency fund to alleviate financial stress. A significant portion of Americans struggle with limited emergency funds, and the $5,000 check can help accelerate reaching this goal, especially for those who have little in savings. Applying a majority of the payout towards high-interest credit card debt can also be a wise move, as it can save you thousands of dollars in interest and accelerate achieving debt freedom.

Consumer Reports assessed the most leading voice cloning tools and found that four products did not have proper safeguards in place to prevent non-consensual cloning. The technology has many positive applications, but it can also be exploited for elaborate scams and fraud. To address these concerns, Consumer Reports recommends additional protections, such as unique scripts, watermarking AI-generated audio, and prohibiting audio containing scam phrases.